膀胱癌分子分型的研究进展

Advances in molecular classification of bladder cancer

膀胱癌是泌尿生殖系统第二常见的恶性肿瘤,仅次于前列腺癌,具有高度异质性,其发生、发展机制涉及多个基因组结构和功能的异常改变。利用分子生物学技术研究膀胱癌的分子分型对明确疾病发病机制、选择治疗方案具有重要意义。现对膀胱癌分子分型的研究进展作一综述。

Bladder cancer is the second most common tumor in the urinary system after prostate cancer.It is highly heterogeneous and its developmental mechanism involves abnormal alterations in the structure and function of multiple genomes.Researching the molecular classification of bladder cancer by using molecular biology techniques is important for defining the pathogenesis of the disease and selecting therapeutic schedule.This paper will review the progress of molecular classification studies of bladder cancer.