肺泡巨噬细胞在慢性肺疾病中作用的研究进展

Research progress on role of alveolar macrophages in chronic lung disease

肺泡巨噬细胞(AMs)作为呼吸树的前哨细胞,也是构成稳定状态下的优势免疫细胞,在防御病原体和耐受无害刺激之间的平衡中发挥重要作用。AMs的不同特征影响着肺部感染、慢性炎症疾病以及肺癌的预后。因此,本文主要通过查阅国内外文献,对AMs与不同慢性肺部疾病中的相关性进行综述,以期为慢性肺病的临床防治提供更多的理论依据。

Alveolar macrophage(AMs),as a sentinel cell in the respiratory tree,is also a dominant immune cell in the stable state,playing an important role in the balance between defense against pathogens and tolerance to harmless stimuli.Different characteristics of alveolar macrophages affect the prognosis of lung infections,chronic inflammatory diseases,and lung cancer.Therefore,this paper mainly reviewes the correlation between alveolar macrophages and different chronic lung diseases by reviewing domestic and foreign literature,in order to provide more theoretical basis for the clinical prevention and treatment of chronic lung diseases.