多模态磁共振成像在前列腺外周带癌诊断中的应用价值分析

Application Value of Multimodal Magnetic Resonance Imaging in the Diagnosis of Peripheral Prostate Cancer

目的研究分析多模态磁共振成像在前列腺外周带癌诊断中的应用价值。方法选取于2019年1月-2021年12月期间,我院收治的前列腺外周带可疑病灶患者58例,经过病理学检查确定,有前列腺外周带癌患者25例;前列腺增生及前列腺慢性炎症等良性病变患者33例。所有患者均于穿刺术前行MRI(T1WI、T_(2)WI、DWI、DCE)检查,统计患者MRI检查结果与其病理结果进行对比分析,并通过ROC(受试者工作曲线)从灵敏度、特异度及准确度对多模态磁共振成像技术的诊断效能进行研究。结果58例前列腺外周带可疑病灶患者经T_(2)WI、DWI及DCE-MRI检查后,灵敏度分别为56%、76%、84%;特异度分别为69.70%、81.82%、84.85%;准确度分别为63.79%、79.31%、84.48%;AUC分别为0.628、0.789、0.844。经多模态磁共振成像技术检查后,有前列腺外周带癌26例,前列腺炎32例,对比病理检查结果后得到,多模态磁共振成像对前列腺外周带癌诊断灵敏度:100%、特异度:97.97%、准确度:98.28%、AUC:0..929。结论多模态磁共振成像技术在前列腺外周带癌的临床诊断中具有较高的灵敏性及特异性,有利于临床上筛查出需要进一步进行穿刺活检的前列腺疾病患者提高诊断的准确性。

Objective To study and analyze the application value of multimodal magnetic resonance imaging in the diagnosis of peripheral prostate cancer.Methods 58 patients with suspected lesions in the peripheral zone of prostate treated in our hospital from January 2019 to December 2021 were selected.After pathological examination,25 patients with peripheral zone of prostate cancer were confirmed;33 patients with benign prostatic hyperplasia and chronic prostatic inflammation.All patients were examined by MRI(T1WI,T_(2)WI,DWI,DCE)before puncture.The MRI results were compared with their pathological results,and the diagnostic efficiency of multimodal magnetic resonance imaging was studied from the sensitivity,specificity and accuracy through ROC(subject working curve).Results after T_(2)WI,DWI and DCE-MRI,the sensitivity of 58 patients with suspicious lesions in the peripheral zone of prostate were 56%,76%and 84%,respectively;The specificity was 69.70%,81.82%and 84.85%,respectively;The accuracy was 63.79%,79.31%and 84.48%respectively;AUC was 0.628,0.789 and 0.844 respectively.After multimodal magnetic resonance imaging,there were 26 cases of peripheral prostate cancer and 32 cases of prostatitis.Compared with the results of pathological examination,the sensitivity,specificity,accuracy and AUC of multimodal magnetic resonance imaging in the diagnosis of peripheral prostate cancer were 100%,97.97%,98.28%and 0.929 respectively.Conclusion multimodal magnetic resonance imaging has high sensitivity and specificity in the clinical diagnosis of peripheral prostate cancer.It is helpful to screen patients with prostate diseases who need further puncture biopsy and improve the accuracy of diagnosis.