慢加急性肝衰竭的预后评价

Prognostic evaluation of acute-on-chronic liver failure

慢加急性肝衰竭(ACLF)是临床常见的严重肝病临床症候群,短期病死率高。因此,早期准确评估ACLF患者预后,对临床决策及改善患者预后具有十分重要的意义。本文就近年来ACLF预后评价标志物的研究进展进行综述,旨在完善现有的预后评价体系,帮助临床医生及时给予适当的临床干预措施,进而降低患者病死率。

Acute-on-chronic liver failure(ACLF)is a common clinical syndrome of severe liver disease characterized by a high short-term mortality rate in clinical practice.Therefore,early and accurate evaluation of the prognosis of ACLF patients is of great significance for making clinical decisions and improving prognosis.This article reviews the recent research advances in markers for the prognostic evaluation of ACLF,in order to improve the existing prognostic evaluation system,assist clinicians in providing timely and appropriate clinical intervention,and further reduce the mortality rate of patients.