X-yne click polymerization

Alkyne-based click polymerizations have been nurtured into a powerful synthetic technique for the preparation of new polymers with advanced structures and versatile properties.Among them,the emerging thiol-yne,hydroxyl-yne,and amino-yne click polymerizations have made remarkable progress from reactions to applications.These polymerizations avoid the usage of inherently dangerous monomers and are safer to operate than the classical azide-alkyne click polymerization(AACP),making them more prospective for diverse applications.To greatly promote the new alkyne-based click polymerizations beyond AACP,a new concept of“X-yne click polymerization”is proposed to unify them,where“X”denotes the monomers that can react with alkynes under mild reaction conditions,including thiols,alcohols,amines,and other promising ones.In this review,we mainly present a brief account of the progress of X-yne click polymerization and discuss in detail the challenges and opportunities in this field.