腹腔镜在结直肠癌根治术中的应用效果

Application Effect of Laparoscopy in Colorectal Cancer Radical Surgery

目的:分析结直肠癌根治术中应用腹腔镜的临床疗效。方法:选取2019年4月—2022年10月徐州市铜山区中医院收治的结直肠癌患者72例作为研究对象,根据随机数字表法分为对照组与观察组,各36例。对照组采取传统开腹根治术,观察组采取腹腔镜根治术。比较两组围术期指标、应激指标及术后并发症发生情况。结果:观察组手术时间长于对照组,切口小于对照组,术中出血量少于对照组,术后4 h疼痛评分低于对照组,术后排气时间及术后住院时间短于对照组,差异有统计学意义(P<0.001)。术后4 h,两组皮质醇(Cor)、C反应蛋白(CRP)水平均高于术前,但观察组低于对照组,差异有统计学意义(P<0.05);术后24 h,两组Cor、CRP水平均低于术后4 h,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组术后并发症发生率低于对照组,差异有统计学意义(P=0.013)。结论:腹腔镜在结直肠癌根治术中的应用效果显著,可减轻患者创伤、疼痛及手术应激反应,促进患者恢复,降低并发症发生率。

Objective:To analyze the clinical efficacy of laparoscopy in radical surgery of colorectal cancer.Methods:A total of 72 patients with colorectal cancer admitted to Suzhou Tongshan Hospital of Traditional Chinese Medicine from April 2019 to October 2022 were selected as the study subjects.They were divided into control group and observation group according to random number table method,with 36 cases in each group.The control group received traditional open surgery and the observation group received laparoscopic radical surgery.The perioperative indexes,stress indexes and postoperative complications were compared between the two groups.Results:The operation time in the observation group was longer than that in the control group,the incision in the observation group was smaller than that in the control group,the intraoperative blood loss in the observation group was less than that in the control group,the pain score at 4 h after surgery in the observation group was lower than that in the control group,and the postoperative exhaust time and postoperative hospital stay in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.001).At 4 h after surgery,the levels of cortisol(Cor)and C-reactive protein(CRP)in the two groups were higher than those before surgery,but the observation group was lower than the control group,and the difference was statistically significant(P<0.05).At 24 h after surgery,the levels of Cor and CRP in two groups were lower than those at 4 h after surgery,and the observation group was lower than the control group,and the difference was statistically significant(P<0.05).The incidence of postoperative complications in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.013).Conclusion:The application effect of laparoscopy in radical surgery of colorectal cancer is remarkable,which can alleviate the trauma,pain and surgical stress reaction of patients,promote recovery and reduce the incidence of complications.