睡眠参数与男性性功能障碍的相关性研究

Correlation between sleep parameters and male sexual dysfunction

目的 探究睡眠参数与男性性功能障碍的相关性,为临床上男性性功能障碍患者的诊治提供帮助。方法 选取2023年1月至3月在江苏省中医院男科就诊的52例性功能障碍的男性患者为患者组,同时入组27例性功能正常的男性为正常组,性功能障碍的判断采用亚利桑那性体验量表(Arizona Sexual Experience Scale,ASEX)。所有受试者在入院第1天收集一般资料及实验室检验数据,并填写症状检查表90 (Symptom Checklist 90,SCL-90)。受试者通过左手腕佩戴小米手环6来监测睡眠,收集入院第2晚睡眠参数。比较两组间的一般资料、实验室数据、量表评分及睡眠参数,并进行相关性分析。结果 一般资料及检验数据方面,正常组的睾酮高于患者组,差异有统计学意义;SCL-90评分方面,正常组的精神病性、躯体化及抑郁的评分低于患者组,差异有统计学意义;睡眠参数方面,正常组的总快速眼动(rapid eye movement,REM)睡眠时间长于患者组,差异有统计学意义。相关性方面,总REM睡眠时间与年龄负相关,总REM睡眠时间与体质指数呈负相关,总REM睡眠时间与ASEX总分负相关,有统计学意义。结论 睡眠参数与男性性功能障碍存在一定的相关性,REM睡眠的不足可能参与男性性功能障碍的发生发展。

Objective To investigate the association between sleep parameters and male sexual dysfunction,hoping to improve clinical diagnosis and treatment of patients with sexual dysfunction.Methods In 2023,a total of 52 male patients with sexual dysfunction were enrolled in the Male Department of Jiangsu Provincial Hospital of Traditional Chinese Medicine from January to March.In addition,27 male patients with normal sexual function were enrolled as controls.The diagnosis of sexual dysfunction was determined by using the Arizona Sexual Experience Scale(ASEX).Data on general health and blood tests were collected and the Symptom Checklist 90(SCL-90)was completed.To monitor sleep and collect sleep parameters,participants wore a Mi Band 6 on their left wrist.General health data,test results,scale scores,and sleep parameters were compared between the two groups.Results Compared to the patient group,the levels of testosterone were significantly higher in the normal group.Additionally,the scores for psychosis,somatization,and depression on the SCL-90 scale were also significantly lower in the normal group compared to the patient group.Regarding sleep parameters,total REM sleep time was significantly higher in the normal group than that in the patient group.Additionally,there was a negative correlation between total REM sleep time and age,body mass index,and the total score of ASEX with significant difference.Conclusions Sleep parameters may be correlated with male sexual dysfunction.Deficiency or disorder in REM sleep might contribute to the development of male sexual dysfunction.