老年急性消化道出血患者合并下肢深静脉血栓的相关危险因素分析

Analysis of related risk factors of lower extremity deep vein thrombosis in elderly patients with acute gastrointestinal hemorrhage

目的探讨老年急性消化道出血患者合并下肢深静脉血栓(DVT)的相关危险因素。方法收集2019年3月至2022年12月首都医科大学附属北京友谊医院收治的96例老年急性消化道出血患者的临床资料。根据是否合并下肢DVT将患者分为血栓组(n=21)和对照组(n=75)。分析老年急性消化道出血患者合并下肢DVT的相关危险因素。结果血栓组患者的年龄、合并恶性肿瘤的比例、D-二聚体水平均高于对照组患者,服用阿司匹林的比例低于对照组患者,差异均有统计学意义(P﹤0.05)。多因素分析结果显示,年龄≥80岁、未服用阿司匹林、合并恶性肿瘤、D二聚体水平﹥1000μg/L均是老年急性消化道出血合并下肢DVT的危险因素(P﹤0.05)。结论年龄≥80岁、未服用阿司匹林、合并恶性肿瘤、D二聚体水平﹥1000μg/L均会增加老年急性消化道出血患者合并下肢DVT的风险,临床中应注意对此类患者进行密切筛查。

Objective To explore the related risk factors of lower extremity deep vein thrombosis(DVT)in elderly patients with acute gastrointestinal hemorrhage.Method Clinical data of 96 elderly patients with acute gastrointestinal hemorrhage admitted to the Beijing Friendship Hospital,Capital Medical University from March 2019 to December 2022 were collected.The patients were divided into thrombosis group(n=21)and control group(n=75)according to whether they were complicated with lower extremity DVT.The relatde risk factors of lower extremity DVT in elderly patients with acute gastrointestinal hemorrhage were analyzed.Result The age,proportion of patients with concomitant malignant tumor and D-dimer level in thrombosis group were higher than those in control group,and the proportion of patients taking aspirin was lower than that in control group,the differences were statistically significant(P<0.05).Multivariate analysis showed that age≥80 years old,not taking aspirin,concomitant malignant tumors,and D-dimer>1000μg/L were independent risk factors of lower extremity DVT in elderly patients with acute gastrointestinal hemorrhage(P<0.05).Conclusion Age≥80 years old,not taking aspirin,concomitant malignant tumors,D-dimer>1000μg/L can increase the risk of lower extremity DVT in elderly patients with acute gastrointestinal hemorrhage,and the patients should be closely screened in clinical practice.