摘要
经导管动脉化疗栓塞术(transcatheter arterial chemoembolization,TACE)是目前抗肿瘤治疗常用的方法,手术的成功很大程度上依赖于栓塞剂的选择。温敏性水凝胶是一种具有特殊结构、温度刺激下的溶胶-凝胶相变及良好生物相容性的新型液体栓塞剂。文章就温敏性水凝胶的特点及其作为栓塞剂在TACE治疗中的应用进展进行系统总结和论述,并浅析了目前的挑战与前景。
Transcatheter arterial chemoembolization(TACE)is a currently common approach to antitumor therapy,in which procedural success depends heavily on the choice of embolic agent.Temperature-sensitive hydrogel is a novel liquid embolic agent with special structure,temperature-stimulated sol-gel phase transition and excellent biocompatibility.This review systematically summarized and discussed the characteristics of temperature-sensitive hydrogel and its application progress as embolic agent for TACE therapy,and briefly analyzed the existing challenges and prospects.
作者
葛校永
李亚华
李宗明
周子鹤
吴昆鹏
李一帆
韩新巍
任克伟
Xiaoyong Ge;Yahua Li;Zongming Li;Zihe Zhou;Kunpeng Wu;Yifan Li;Xinwei Han;Kewei Ren(Department of Interventional Radiology,the First Affiliated Hospital of Zhengzhou University;Engineering Technology Research Center for Minimally Invasive Interventional Tumors of Henan Province,Henan Zhengzhou 450052,China)
出处
《中华介入放射学电子杂志》
2023年第3期268-274,共7页
Chinese Journal of Interventional Radiology:electronic edition
基金
河南省科技厅中原学者工作站资助项目(234400510027)。
关键词
温敏性水凝胶
经导管动脉化疗栓塞术
肿瘤
Temperature-sensitive hydrogel
Transcatheter arterial chemoembolization
Tumor