摘要
Comprehensive Summary The radical-mediated reductive functionalization of aryl halides has been extensively studied.However,the related radical-mediated intermolecular reductive 1,2-diarylation of alkenes,using aryl halides as aryl radical sources,remains unexplored.Herein,a new electrophotocatalytic intermolecular reductive 1,2-diarylation of alkenes is reported using aryl halides and cyanoaromatics to produce polyarylated alkanes.Using synergistic cathodic reduction and visible-light photoredox catalysis,various electron-rich and electron-deficient aryl halides are combined with various alkenes and cyanoaromatics to characterize the broad substrate scope,excellent functional group compatibility,and excellent selectivity of this reaction.Mechanistic investigations reveal that this reaction may proceed via a radical process initiated by the reductive generation of aryl radicals from aryl halides and terminated by radical-radical coupling with cyanoaromatic radical anions.
基金
the National Natural Science Foundation of China(Nos.21871126 and 22271245)
the Jiangxi Province Science and Technology Project(Nos.20212AEi91002 and 20224BAB213013)
the Jiangxi Educational Committee Foundation of China(GJJ210906)
the Open Research Fund of the School of Chemistry and Chemical Engineering,Henan Normal University(No.2021zD01)for theirfinancial support.
