2016-2022年江苏省苏州市丙型肝炎流行病学特征分析

Epidemiological characteristics of hepatitis C in Suzhou,Jiangsu,2016−2022

目的分析2016—2022年江苏省苏州市丙型肝炎(丙肝)的流行特征,为丙肝防控提供线索依据。方法搜集并整理2016—2022年苏州市丙肝报告病例,进行流行病学描述,分析苏州市丙肝病例三间(时间、空间、人群)分布。采用χ^(2)检验对不同组别发病差异进行分析。结果2016—2022年苏州市累计发病2777例,年均发病率3.14/10万,发病率呈逐年上升趋势。苏州市丙肝发病无季节性,季节性差异无统计学意义(M值=0.100)。苏州市主城区丙肝发病率高于非主城区,其中姑苏区丙肝发病数(540例)与发病率(8.11/10万)最高。男性年均发病率(3.27/10万)高于女性年均发病率(3.00/10万),差异有统计学意义(χ^(2)=4.832,P=0.028);65~岁组年均发病率(5.08/10万)高于15~64岁组年均发病率(3.37/10万),差异有统计学意义(χ^(2)=76.603,P<0.001)。职业分布主要集中在家务及待业人员(33.71%)、农民(19.81%)、工人(14.76%)、商业服务(13.90%)、离退人员(12.71%)。结论2016—2022年苏州市丙肝发病率呈上升趋势,无季节性差异,存在明显地区和人群差异,姑苏区丙肝高发。应继续规范医院丙肝病例报告,加强对高发地区、重点人群的病例筛查和宣传教育。

Objective To analyze the epidemiological characteristics of hepatitis C in Suzhou from 2016 to 2022,and provide evidence for the prevention and control of hepatitis C.Methods The incidence data of hepatitis C in Suzhou from 2016 to 2022 were collected for a descriptive epidemiological analysis on the distributions of hepatitis C cases in Suzhou.The differences in incidence of hepatitis C among different groups were compared withχ^(2)test with P<0.05 indicating significant difference.Results From 2016 to 2022,a total of 2777 cases of hepatitis C were reported in Suzhou,with an incidence rate of 3.14/100000,showing an increasing trend by year.Hepatitis C was reported all the year round with no obvious seasonality(M=0.100).The incidence of hepatitis C was higher in main urban area than that in non-main urban area.The case number and incidence rate of hepatitis C were highest in Gusu district(540 cases,8.11/100000).The average annual incidence rate was higher in men(3.27/100000)than in women(3.00/100000),the difference was significant(χ^(2)=4.832,P=0.028).The average annual incidence rate was higher in people aged 65–years(5.08/100000)than in people aged 15–64 years(3.37/100000),and the difference was significant(χ^(2)=76.603,P<0.001).The cases were mainly the jobless or unemployed(33.71%),farmers(19.81%),workers(14.76%),people engaged in business services(13.90%)and retirees(12.71%).Conclusion From 2016 to 2022,the overall incidence of hepatitis C in Suzhou showed a rise trend.The incidence of hepatitis C showed no seasonality in Suzhou,but the differences in hepatitis C incidence among areas and populations were significant.The incidence of hepatitis C was high in Gusu district.It is necessary to standardize the reporting of hepatitis C in hospitals and strengthen case screening and health education in key populations in areas with high incidence of hepatitis C.