非酒精性脂肪肝患者运动管理的最佳证据总结

The best evidence summary of exercise management of patients with nonalcoholic fatty liver disease

目的检索并汇总非酒精性脂肪肝患者运动管理的相关证据,为临床提供参考。方法系统检索UpToDate、BMJ Best Practice、国际指南协作网、苏格兰学院指南网、英国国家卫生与临床优化研究所网站、Cochrane Library、美国医疗保健研究与质量局网站、加拿大安大略注册护士协会网站、美国肝病研究学会网站、PubMed、Web of Science、CINAHL、DynaMed、Embase、中国医脉通指南网、中国知网、中华医学期刊全文数据库、万方数据知识服务平台、中国生物医学文献数据库中关于非酒精性脂肪肝患者运动管理的所有证据,包括指南、证据总结、专家共识、最佳临床实践、临床决策、推荐实践、系统评价,检索时限为建库至2022年11月。由2名研究者独立对文献进行质量评价。结果共纳入系统评价、专家共识、指南18篇文献,从运动原则、运动监督、运动类型、运动选择、运动时间与频率、运动强度等6个方面汇总24条最佳证据。结论该研究汇总的非酒精性脂肪肝患者运动管理的最佳证据具有全面性和科学性,医护人员可以通过应用最佳证据指导非酒精性脂肪肝患者合理运动,提高干预科学性。

Objective To search and obtain relevant evidence of exercise management in patients with nonalcoholic fatty liver disease(NAFLD)and to provide a reference for clinical practice.Methods UpToDate,BMJ Best Practice,International Guidelines Collaboration(GIN),Scottish College Guidelines Network(SIGN),National Institute for Healthcare Excellence(NICE)website,Cochrane Library,U.S.Agency for Healthcare Research and Quality(AHRQ)website,Canadian Association of Registered Nurses of Ontario(RNAO)website,American Association for the Study of Liver Diseases(AASLD)website,PubMed,Web of Science,CINAHL,DynaMed,Embase,CNKI,Chinese Medical journal full-text database,Wanfang Data Knowledge Service Platform,Sinomed and other databases were systematically searched for all evidence on exercise management of the NAFLD.It includes guidelines,evidence summaries,expert consensuses,best practice information booklets,clinical decisions,recommended practice,and systematic reviews.The retrieval period is from the database inception to November 2022.The quality of the literature was evaluated independently by 2 researchers.Results A total of 18 pieces of literature,including systematic evaluations,expert consensuses,and clinical practice guidelines,were included.24 pieces of best evidence were collected from 6 aspects,including exercise principle,exercise supervision,exercise type,exercise selection,exercise time and frequency,and exercise intensity.Conclusion This study summarized the best evidence for exercise management of patients with NAFLD,which is comprehensive and scientific.Medical staff can use the best evidence to guide patients with NAFLD to exercise reasonably and improve the scientific nature of the intervention.