陕西省成年人睡眠状况与糖尿病的关联研究

Association between sleep status and diabetes mellitus among adults in Shaanxi Province

目的探讨陕西省成年人睡眠时间和睡眠质量与糖尿病之间的关联,为糖尿病预防与控制提供依据。方法通过多阶段分层整群随机抽样方法,选取2018年陕西省成人慢性病及危险因素监测项目中18岁及以上常住居民6202人为研究对象,进行问卷调查、体格检查和实验室检测。通过多因素logistic回归分析模型分析睡眠时间和睡眠质量与糖尿病患病的独立和联合关联。结果共纳入6062名研究对象,糖尿病患病率为8.17%。多因素logistic回归分析模型分析结果显示,调整相关混杂因素后,与睡眠时间6~<8 h/d组相比,睡眠时间<6 h/d组(OR=1.38,95%CI:1.07~1.78,P=0.014)和>8 h/d组(OR=1.26,95%CI:1.05~1.52,P=0.015)患糖尿病的风险增大。与睡眠质量好组相比,睡眠质量差组(OR=1.32,95%CI:1.09~1.61,P=0.005)患糖尿病的风险增大。将睡眠时间和质量组合后进一步分析结果显示,与睡眠时间6~<8 h/d且睡眠质量好组相比,睡眠时间<6 h/d且睡眠质量差组(OR=1.55,95%CI:1.14~2.10,P=0.005)和睡眠时间>8 h/d且睡眠质量差组(OR=1.53,95%CI:1.18~1.99,P=0.002)患糖尿病的风险增大。结论睡眠时间异常和睡眠质量差均与糖尿病患病相关,且二者存在联合效应。

Objective To explore the associations of sleep duration and sleep quality with diabetes mellitus among adults in Shaanxi Province,thus providing evidence for diabetes prevention and control.Methods Through multi-stage stratified cluster random sampling method,6202 permanent residents aged 18 years and older were selected as research subjects from Shaanxi Adult Chronic Disease and Risk Factor Surveillance Program in 2018.Questionnaire survey,physical examination and laboratory test were conducted.Multivariate logistic regression analysis model analysis was used to analyze the independent and combined associations between sleep duration,sleep quality and diabetes mellitus.Results A total of 6062 subjects were enrolled in this analysis,and the prevalence of diabetes was 8.17%.The results of multivariate logistic regression analysis model analysis showed that after adjusting for relevant confounding factors,compared with the sleep duration of 6 to<8 h/d group,the risk of diabetes increased in the sleep duration<6 h/d group(OR=1.38,95%CI:1.07-1.78,P=0.014)and the>8 h/d group(OR=1.26,95%CI:1.05-1.52,P=0.015).Compared with the group with good sleep quality,the group with poor sleep quality(OR=1.32,95%CI:1.09-1.61,P=0.005).had an increased risk of diabetes.Further analysis of the combination of sleep duration and quality showed that compared with the group with sleep duration of 6-<8 h/d and good sleep quality,those with sleep duration<6 h/d and poor sleep quality(OR=1.55,95%CI:1.14-2.10,P=0.005)and those with sleep duration>8 h/d and poor sleep quality(OR=1.53,95%CI:1.18-1.99,P=0.002)had an increased risk of diabetes.Conclusions Both abnormal sleep duration and poor sleep quality are associated with diabetes mellitus,and a joint effect exists between them.