MSCT联合MRI早期诊断肺癌患者的效能及对临床治疗的指导作用研究

Study on the efficacy of MSCT combined with MRI in early diagnosis of lung cancer patients and its guiding effect on clinical treatment

目的研究多层螺旋CT(MSCT)联合磁共振成像(MRI)早期诊断肺癌患者的效能及对临床治疗的指导作用。方法选取南京医科大学附属无锡人民医院从2021年2月-2023年1月收治的114例疑似肺癌患者作为研究对象。所有患者均接受MSCT与MRI检查。以手术病理检查结果为金标准,对比肺癌与良性病变患者MSCT征象、MRI图像参数,分析MSCT联合MRI诊断肺癌的效能。结果114例疑似肺癌患者经手术病理检查结果显示肺癌52例,良性病变62例。肺癌患者病灶大小≥3cm、病灶边缘毛刺、病灶外缘分叶、胸膜凹陷征、血管集束征、淋巴结肿大及CT增强强化≥30HU人数占比均高于良性病变患者(均P<0.05)。肺癌患者T2-Q、DWI-LSR及ADC-LSR均高于良性病变患者(均P<0.05)。将病理诊断结果视作金标准,MSCT、MRI及二者联合分别检出肺癌50例、50例、51例。MSCT联合MRI诊断肺癌的灵敏度、特异度及准确性分别为94.23%、96.77%、95.61%,均高于MSCT的73.08%、80.65%、77.19%与MRI的76.92%、83.87%、80.70%(均P<0.05)。结论MSCT联合MRI早期诊断肺癌患者的效能较佳,可为临床治疗提供影像学依据,值得推广应用。

Objective To investigate the efficacy of multi-slice spiral CT(MSCT)combined with magnetic resonance imaging(MRI)in early diagnosis of lung cancer patients and its guiding role in clinical treatment.Methods 114 suspected lung cancer patients admitted from February 2021 to January 2023 were selected as subjects.All patients underwent MSCT and MRI.Using the results of surgical pathological examination as the gold standard,MSCT signs and MRI image parameters of patients with lung cancer and benign lesions were compared to analyze the efficacy of MSCT combined with MRI in the diagnosis of lung cancer.Results There were 52 cases of lung cancer and 62 cases of benign lesions in 114 suspected lung cancer patients.The proportions of patients with lung cancer with lesion size≥3cm,lesion edge burr,peripheral lobe,pleural depression sign,vascular cluster sign,lymph node enlargement and CT enhancement≥30HU were all higher than those with benign lesions(all P<0.05).T2-Q,DWI-LSR and ADC-LSR in lung cancer patients were higher than those in benign lesions(all P<0.05).With pathological diagnosis as the gold standard,50 cases of lung cancer were detected by MSCT,50 cases by MRI and 51 cases by MRI.The sensitivity,specificity and accuracy of MSCT combined with MRI in the diagnosis of lung cancer were 94.23%,96.77%and 95.61%,which were higher than that of MSCT(73.08%,80.65%,77.19%)and MRI(76.92%,83.87%,80.70%)(all P<0.05).Conclusion MSCT combined with MRI has better efficacy in early diagnosis of lung cancer patients,which can provide imaging basis for clinical treatment,and is worth popularizing and applying.