上海市市售婴幼儿配方乳粉中壬基酚的膳食暴露评估

Assessment of dietary exposure to nonylphenol in infant formula retailed in Shanghai

【目的】评估上海市0~36月龄婴幼儿配方乳粉壬基酚膳食暴露的健康风险。【方法】于2022年开展上海市市售婴幼儿配方乳粉中壬基酚污染的风险监测,共监测90件样品,样品分别来自上海市的母婴店、超市以及网店。结合每日婴幼儿配方乳粉的消费数据,采用点评估法对婴幼儿配方乳粉中壬基酚进行膳食暴露评估。【结果】上海市售婴幼儿配方乳粉中壬基酚检出率为95.6%(86/90),壬基酚含量范围为未检出~22.70μg·kg^(-1),含量均值为8.47μg·kg^(-1),P_(50)为7.77μg·kg^(-1)。上海市0~6月龄、7~12月龄以及13~36月龄的婴幼儿每日通过配方乳粉摄入壬基酚的平均暴露量(按体质量计)分别为0.091、0.068和0.054μg·kg^(-1),P_(95)每日暴露量(按体质量计)分别为0.228、0.152和0.119μg·kg^(-1),均远低于壬基酚每日耐受摄入量(按体质量计5μg·kg^(-1))。【结论】上海市0~36月龄婴幼儿每日通过婴幼儿配方乳粉摄入壬基酚造成的健康风险较低。

[Objective]To assess the health risk of dietary exposure to nonylphenol in infants aged 0-36 months through infant formula in Shanghai.[Methods]A monitoring of nonylphenol pollution in infant formula was conducted in 2022.A total of 90 samples were obtained from maternal and infant stores,supermarkets,and online stores in Shanghai.Based on the daily consumption data of infant formula,a point assessment method was used to assess the dietary exposure to nonylphenol in infant formula.[Results]The prevalence of nonylphenol in infant formula retailed in Shanghai was 95.6%(86/90).The amount of nonylphenol varied from non-detected to 22.70μg·kg^(−1),with the mean value of 8.47μg·kg^(−1) and the P50 value of 7.77μg·kg^(−1).The mean daily nonylphenol exposure(estimated by body weight)from infant formula in infants aged 0−6 months,7−12 months and 13−36 months in Shanghai was 0.091,0.068 and 0.054μg·kg^(−1),respectively;furthermore,the P95 value of daily exposure(by body weight)was 0.228,0.152 and 0.119μg·kg^(−1),respectively.These amounts were much lower than the tolerable daily intake(TDI)of nonylphenol(by body weight 5μg·kg^(−1)).[Conclusion]The health risk of daliy nonylphenol intake from infant formula remains low among infants aged 0−36 months in Shanghai.