基于伤残调整寿命年的2010年和2020年四川省疾病负担比较分析

Comparative analysis of disease burden in Sichuan Province in 2010 and 2020 based on disability-adjusted life years

【目的】分析2010年和2020年四川省疾病负担,为疾病防治提供决策参考。【方法】收集2010年和2020年四川省死因监测数据,计算伤残调整生命年(DALY)、早死寿命损失年(YLL)和伤残寿命损失年(YLD)来评估四川省疾病负担。【结果】2020年DALY为700.40万人年,其中YLL和YLD分别为371.96万人年、328.44万人年。与2010年比较,2020年DALY增长了8.27%,其中大部分来自YLL的增长(16.66%)。2020年DALY标化率为69.91‰,较2010年降低了9.87%,其中女性降低了15.87%,男性降低了5.28%。≥60岁老年人2020年的DALY疾病负担较2010年增长了34.55%。传染病和母婴疾病的负担降低幅度最大,2020年男性和女性DALY标化率分别较2010年下降了47.03%、55.50%。其次为损伤,男性和女性分别降低了32.97%、26.92%。慢性病DALY标化率男性增长了5.41%,女性降低了10.67%。2020年男性DALY标化率较2010年增加显著的疾病为糖尿病(82.02%)、神经系统和精神障碍疾病(26.31%)和心脑血管疾病(19.86%);女性增加显著的疾病为糖尿病(54.74%)、神经系统和精神障碍疾病(35.52%)、肌肉骨骼和结缔组织病(23.51%)。【结论】四川省疾病负担整体呈现下降趋势,主要来自传染病和母婴疾病和损伤的降低。≥60岁老年人的疾病负担增长明显,重点控制疾病为糖尿病、心脑血管疾病、神经系统和精神障碍疾病、肌肉骨骼和结缔组织病等慢性病。

[Objective] To analyze the disease burden in Sichuan Province in 2010 and 2020,and to provide reference for disease prevention and control.[Methods] Monitoring data on causes of death in Sichuan Province in 2010 and 2020 were collected.Disability-adjusted life years(DALY),years of life lost(YLL) and years lived with disability(YLD) were calculated to assess the disease burden in Sichuan Province.[Results] In 2020,DALY was 7.004 0 million years,among which YLL and YLD were 3.719 6 million and 3.284 4 million,respectively.Compared with 2010,the total DALY in 2020 increased by 8.27%,most of which came from the increase of YLL(16.66%).In 2020,the standardized total DALY rate was 69.91‰,which decreased by 9.87% compared with 2010.Specifically,the rate decreased by 15.87% for females and 5.28% for males.In 2020,the burden of DALY disease in the elderly over 60 years old increased by 34.55% compared with 2010.The burden of infectious and maternal diseases decreased the most,and the standardized DALY rates of male and female in 2020 decreased by 47.03% and 55.50% compared with 2010,respectively.Injury was the next most important factor,which decreased by 32.97% in males and 26.92% in females.The standardized DALY rate of chronic diseases increased by 5.41% in males and decreased by 10.67% in females.In 2020,compared with 2010,the standardized DALY rate of males increased significantly in diabetes(82.02%),nervous system and mental disorders(26.31%),and cardiovascular and cerebrovascular diseases(19.86%).Among women,significant increases were seen in diabetes mellitus(54.74%),neurological and mental disorders(35.52%),and musculoskeletal and connective tissue diseases(23.51%).[Conclusion] The overall disease burden in Sichuan Province shows a declining trend,mainly attributed to the decrease in infectious and maternal diseases and injuries.The disease burden among people over 60 years old has increased significantly,with the focus on chronic diseases such as diabetes,cardiovascular and cerebrovascular diseases,nervous system and mental disorders,and musculoskeletal and connective tissue diseases.