妊娠期鼻炎患者临床治疗及用药方案的研究进展

Research progress in the clinical treatment and drug regimen for patients with pregnancy rhinitis

鼻炎有多种治疗方法,但针对妊娠期鼻炎的治疗及用药方案的研究相对较少。处于妊娠期的机体各个系统会发生明显的适应性改变,并且药物的药代动力学和药效变化与非妊娠期也有着明显的差异,某些药物还可通过胎盘屏障,对胚胎、胎儿甚至新生儿造成不良影响。所以,针对妊娠期鼻炎患者医疗方案的选择需慎重考虑。常用于治疗鼻炎的药物有皮质类固醇类药物、减充血剂、抗组胺类药物、色酮类药物以及抗胆碱能药物等,研究上述药物对于妊娠期鼻炎患者的疗效及安全性具有非常重要的意义。论文将妊娠期鼻炎的相关研究进展作介绍,重点评估目前对于妊娠期鼻炎的临床治疗及用药方案。

Although various treatment options are available for rhinitis,research on the treatment and medication regimen for patients suffering from pregnancy rhinitis is relatively scant.In pregnant patients,the pharmacokinetics and pharmacodynamics of drugs differ significantly from those in non-pregnant patients.Some drugs may cross the placental barrier and cause adverse effects on the embryo,fetus,and even in the newborn.Therefore,the choice of medical regimen for patients with pregnancy rhinitis needs careful consideration.Corticosteroids,decongestants,antihistamines,chromones,and anticholinergics are commonly used for treating rhinitis,and it is important to study their efficacy and safety in patients with pregnancy rhinitis.In this article,we present research update on pregnancy rhinitis,with a focus on evaluating the current clinical treatment and medication regimen for patients with this condition.