重症监护病房床旁病原学快速诊断-快速现场微生物学评价

Rapid on-site pathogen diagnosis of intensive care unit: Microbiological Rapid On-Site Evaluation

脓毒症相关死亡占全球总死亡人数比例超过50%, 是威胁公共卫生健康的首要问题。血培养是临床常用确诊脓毒症的方法, 然而其耗时长、易受抗菌药物影响, 尚无法满足快速明确病原的需求。快速现场微生物学评价技术(M-ROSE)是有效快速诊断的方法之一。作为呼吸感染性疾病诊断的辅助手段, M-ROSE在评价标本质量、辅助诊断感染病原、动态监测疗效等方面具有显著优势, 能够助力脓毒症患者的早期病原学诊断。在临床中应密切结合实际情况, 实现M-ROSE效益最大化。

Sepsis-related deaths account for more than 50%of the total deaths in the world and are the primary problem threatening public health.Timely and rapid diagnosis is the key to improving the survival rate of patients with sepsis.Blood culture is a commonly used method to diagnose sepsis in clinics.However,it is time-consuming and unstable,which cannot used for pathogen quickly identification.In recent years,Microbiological rapid on-site evaluation(M-ROSE)based on morphological technique is applying to the clinics,showing significant advantages in timeliness and convenience,which would overcome the shortcomings of traditional diagnostic methods and be conducive to diagnosis of sepsis.