双胎输血综合征临床研究进展

Clinical research progress of twin-twin transfusion syndrome

双胎输血综合征(TTTS)是单绒毛膜双胎妊娠中的一种较为常见且严重的并发症,其发生率约为10%~15%,若不进行及时有效的干预将导致严重的并发症。目前,临床治疗TTTS的最常见方法为胎儿镜下胎盘血管交通支凝固术,大大提高了这类患者的预后,但仍会造成胎死宫内、胎膜早破及早产等术后常见并发症,并对胎儿的预后造成影响,因而需要通过改善手术方式、手术技巧、重视术后管理等方式来减少术后并发症的发生,同时需加强新生儿的出生后的长期随访,关注术后远期并发症。现就TTTS临床诊断、治疗、术后并发症预防、术后管理以及长期随访等予以总结,旨在为临床TTTS诊疗方面提供参考。

Twin-to-twin transfusion syndrome(TTTS)is a common and serious complication in singleton chorionic twin pregnancy,its incidence rate is about 10%to 15%,It may cause serious complications if we don’t take effective interventions in time.At present,the most common treatment for TTTS is coagulation of placental vascular communicating branch under fetoscopy,which greatly improves the prognosis of such patients.However,it still can cause complications such as intrauterine fetal death,premature rupture of membranes and premature delivery,which affect the prognosis of the fetus.Therefore,it is necessary to reduce the occurrence of postoperative complications by improving the operation methods,operation skills,postoperative management and other methods.At the same time,it is also important to take the long-term follow-up of the fetus of such patients after operation.This article summarizes the clinical diagnosis,treatment,prevention of postoperative complications,postoperative management,and long-term follow-up of TTTS,aiming to provide reference for the diagnosis and treatment of TTTS in clinical practice.