原发性醛固酮增多症与阻塞性睡眠呼吸暂停低通气综合征相互作用机制研究进展

Research Progress on the Interaction Mechanism between Primary Aldosteronism and Obstructive Sleep Apnea Hypopnea Syndrome

原发性醛固酮增多症(PA)与阻塞性睡眠呼吸暂停低通气综合征(OSAHS)均是继发性高血压的常见形式之一,可造成全身多处靶器官损伤,是心血管疾病非常重要的危险因素。近年来诸多研究发现,PA患者的OSAHS患病率较高,并认为二者之间可能存在双向关系。本文通过梳理相关文献,总结了PA与OSAHS之间可能存在的相互影响及其机制,以期为PA和OSAHS患者的临床诊治提供新的思路。

Primary aldosteronism(PA)and obstructive sleep apnea hypopnea syndrome(OSAHS)are both common forms of secondary hypertension,which can cause damage to multiple target organs throughout the body and are very important risk factors for cardiovascular disease.In recent years,many studies have found that the prevalence of OSAHS in PA patients is relatively high,and it is believed that there may be a bidirectional relationship between the two.This article summarizes the possible interactions and mechanisms between PA and OSAHS by reviewing relevant literature,in order to provide new ideas for the clinical diagnosis and treatment of PA and OSAHS patients.