摘要
精确、快速的生物医学检测对于更好的健康监测和及时的治疗具有十分重要的作用.因二维(2D)半导体材料具有高灵敏度、高比表面积以及一步电学信号读取等优势,通过将特定探针构筑在其表面,2D晶体管生物传感器具有巨大的优势.尽管研究者们构建出了各类2D晶体管传感器,但它们在单器件级别的性能和功能受到传感界面和晶体管结构设计的限制,且其商业化仍具有挑战.这里,我们概述了晶体管传感器面临的主要挑战,并探讨了应对这些挑战的晶体管传感器设计与开发思路.最后,强调了该类2D晶体管传感系统走向商业化需做出的改进.与其他电学传感器相关技术的发展历程类似,文中所阐述的观点也对生物电子学其他领域的发展具有一定的启示作用.
Understanding biological processes and monitoring health conditions rely on biomedical detection,highlighting the demand of sensing technologies with sufficient precision and sensitivity.The wide-ranging analytes leverage diverse sensing technologies such as spectrometry[1],chromatography[2],nuclear magnetic resonance[3]and other methodologies that have been intensively studied and commercially used.
作者
王学军
魏大程
Xuejun Wang;Dacheng Wei(State Key Laboratory of Molecular Engineering of Polymers,Fudan University,Shanghai 200433,China;Department of Macromolecular Science,Fudan University,Shanghai 200433,China;Laboratory of Molecular Materials and Devices,Fudan University,Shanghai 200433,China)
基金
supported by the National Key R&D Program of China(2021YFE0201400)
the National Natural Science Foundation of China(61890940)
Chongqing Bayu Scholar Program(DP2020036)
the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB30000000)
the Program of Shanghai Academic Research Leaders(23XD1420200)
China Postdoctoral Science Foundation(2019M661353)
the National Postdoctoral Program for Innovative Talents(BX20190072)
the State Key Laboratory of Molecular Engineering of Polymers and Fudan University。
