减重手术在肥胖合并银屑病治疗中的研究进展

Research progress of bariatric surgery in the treatment of obesity with psoriasis

银屑病是一种迁延难愈、并发症多、具有遗传背景的慢性免疫炎症性疾病。文献报道部分患有银屑病的肥胖患者,由于受到肥胖引起的代谢性疾病的困扰,接受了减重手术后,在体重下降、代谢症状改善的同时,银屑病亦得到了较好的缓解,减重手术可能改善银屑病的预后,具体表现为术后银屑病皮损缓解,银屑病治疗药物疗效增加,治疗药物级别下降,银屑病缓解后复发率低。本文就减重手术在肥胖合并银屑病治疗中的研究进展作一综述。

Psoriasis is a chronic immune inflammatory disease with protracted course, many complications and genetic background. It is reported in the literature that some patients with obesity who have psoriasis are troubled by metabolic diseases caused by obesity. After bariatric surgery, psoriasis has also been better alleviated while weight loss and metabolic symptoms have been improved. Bariatric surgery may improve the prognosis of psoriasis,specifically manifested as the relief of psoriasis skin lesions after surgery, the increase of therapeutic efficacy of psoriasis drugs, the decline of therapeutic drug level, and the low recurrence rate of psoriasis after remission. This article reviews the research progress of bariatric surgery in the treatment of obesity complicated with psoriasis.