盲口式无源微流体进样系统流量特性研究

Research on flow characteristics of blind-port passive microfluidic sampling system

为了研究盲口式无源微流体进样系统流量特性,搭建了紧凑型微流体泵送系统,对系统泵送微流体的流量特性进行相应的理论分析,结合实验的方法,验证了理论推导的正确性。首先,分别对5个由不同长度硅胶管搭建的系统进行空载实验,得出系统内部气压与时间的关系呈指数函数的规律衰减;然后,对5个由不同长度硅胶管搭建的系统进行负载实验,并对实验结果进行了分析。研究结果表明:用该系统泵送微流体,其流量范围能够控制在4~23μL/min,该研究在极大程度上简化了微流体泵送系统,并降低实验操作难度,能够满足诸多微流体流量泵送实验的精度要求。

To research on the flow characteristics of the blind-port passive microfluid sampling system,a compact microfluid pumping system is built,and the corresponding theoretical analysis of the flow characteristics of the microfluid pumped by the system is carried out,combined with experimental methods,the correctness of the theoretical derivation is verified.Firstly,the no-load experiment is carried out on five systems built with different lengths of silicone tubes,and it is concluded that the relationship between the internal pressure of the system and the time decays exponentially.Then,the load experiment is carried out on five systems built with different lengths of silicone tubes,and the experimental results are analyzed.The research results show that the flow range of microfluidic pumping with this system can be controlled within 4~23μL/min.This research greatly simplifies the microfluidic pumping system and reduces the difficulty of experimental operation,which can meet the precision requirements of many microfluidics flow pumping experiments.