耳针治疗抑郁症临床疗效的Meta分析

Meta-analysis of Clinical Efficacy of Auricular Acupuncture for Major Depressive Disorder

目的评价耳针治疗抑郁症的临床疗效及安全性。方法通过对万方数据知识服务平台、中国知网、维普资讯中文期刊服务平台、EMBASE、PubMed和Cochrane library数据库进行计算机检索,检索时间段为自建库至2023年2月15日,采用RevMan 5.4对符合纳入标准的文献进行Meta分析。结果目前耳针治疗抑郁症主要以刺激耳穴迷走神经为主。与使用抗抑郁西药的对照组相比,耳针疗法疗效更加显著。与对照组刺激组比较,耳针疗法优于对照组刺激组。结论耳针疗法能够明显降低MDD患者HAMD、BDI、SDS评分,进而改善MDD患者抑郁、焦虑等临床症状,提高生活质量。耳针疗法相对安全有效,无明显不良反应。

Objective To evaluate the clinical efficacy and safety of auricular acupuncture in the treatment of depression.Methods A computerized search of the Wanfang Data Knowledge Service Platform,China Knowledge Network,VipInfo Chinese Journal Service Platform,EMBASE,PubMed,and Cochrane library databases was conducted for the period from the creation of the database to February 15,2023,and Meta-analysis of literature meeting the inclusion criteria was performed using RevMan 5.4.Results The current auricular acupuncture treatment for depression is mainly based on vagus nerve stimulation of auricular points.The effi cacy of auricular acupuncture therapy was comparable compared to the antidepressant western control group.Compared with the control stimulation group,auricular acupuncture therapy was superior to the control stimulation group.Conclusion Ear acupuncture therapy can signifi cantly reduce the HAMD,BDI,and SDS scores of MDD patients,which in turn improves the clinical symptoms of depression and anxiety and improves the quality of life of MDD patients.Ear acupuncture therapy was relatively safe and eff ective,with no signifi cant adverse eff ects.