赵文景教授运用中医药治疗IgA肾病经验撷英

Professor Zhao Wenjing's Experience in Treating IgA Nephropathy with Traditional Chinese Medicine

IgA肾病是全球最常见的原发性肾小球疾病,30%至40%的患者在诊断为IgAN的20~30年后发展为终末期肾病,中医药治疗IgA肾病有一定优势。赵文景教授认为IgA肾病属中医“伏邪致病”范畴,病性属本虚标实,病因责之虚、风、湿、热,核心病机是先天不足,肾阴虚为本,血热为标,伏邪内潜。病位以肾为核心,涉及肺、脾。治疗上以扶助正气、祛除伏邪,标本同治为原则,以益肾填精、清热凉血、益肺固表、健脾利湿、藤药祛风等为主要治法。

Immunoglobulin A nephropathy(IgAN)is the most common primary glomerular disease in the world.Approximately 30%to 40%of cases will progress to endstage kidney disease(ESKD)within 20 to 30 years.Traditional Chinese medicine has certain advantages in the treatment of IgA nephropathy.Professor Zhao Wenjing believes that IgA nephropathy belongs to the category of“Fuxie causing disease”,the nature of disease belongs to deficiency in origin and excess in superficiality,the cause of IgAN belongs to‘deficiency’,‘wind’,‘dampness’,‘heat’,The core pathogenesis is congenital deficiency,kidney-yin deficiency as the root,blood heat as the symptom.The kidney is the core of the disease,involving the lung and spleen.The treatment is based on the principle of supporting healthy qi,dispelling Fuxie and treating both manifestation and root causes,with tonifying the kidney and replenishing essence,clearing heat and cooling blood,tonifying the lung and consolidating the exterior,invigorating the spleen and promoting diuresis,and expelling wind with rattan drugs as the main therapeutic methods.