mRNA疫苗的社会价值评估

Social Value Evaluation of mRNA Vaccines

目的:mRNA疫苗新技术的出现给生物医药企业带来了新的机遇,用定量的方式评价mRNA疫苗的社会价值,以期为其产品的开发提供参考。方法:采用模糊综合评估方法,将mRNA疫苗的社会价值分成正外部性特征价值和负外部性特征影响,将正外部性价值指标分成创新价值、功能性优势、价格优势和其他无形价值,负外部性影响指标则分成对材料的影响、对生产过程的影响、使用或者废弃以后的影响以及对人文环境的影响。同时聘请专家评估社会指标,确定权重并计算社会评价系数。结果:mRNA-1273的社会价值系数为1.84,BNT162b2的社会价值系数为1.98。二者的社会价值系数均远大于1,发展mRNA疫苗总体上利大于弊。结论:mRNA疫苗在生物医药领域具有重要的社会价值,本评估结果可为开发者提供参考,帮助决策者理解其潜在价值,以推动相关技术的进一步发展和应用。

Objective:The emergence of new technologies for mRNA vaccines has brought new opportunities to biopharmaceutical companies.The aim of this article is to evaluate the social value of mRNA vaccines in a quantitative way,as well as to provide references for the development of their products.Methods:Using the fuzzy comprehensive evaluation method,the social value of mRNA vaccines is divided into positive externality characteristic value and negative externality characteristic infl uence,and the positive external characteristic value index is divided into innovation value,functional advantage,price advantage and other intangible value,and the negative external characteristic infl uence index is divided into impact on materials,impact on production process,impact after use or disposal,and impact on human environment.At the same time,experts are hired to evaluate social indicators,determine weights and calculate social evaluation coefficients.Results:The social value coefficient of mRNA-1273 was 1.84,and that of BNT162b2 was 1.98.The social value coefficients of both were much greater than 1,and the overall advantages of developing mRNA vaccines outweighed the disadvantages.Conclusion:mRNA vaccines have important social value in the field of biomedicine.The results of this evaluation can provide a reference for developers and help decision makers understand the potential value,so as to promote the further development and application of related technologies.