结直肠癌发病危险因素研究进展

Risk factors of colorectal cancer

近年来,消化道肿瘤的发生率居高不下,其中结直肠癌(CRC)发病率和病死率不断升高,且呈年轻化趋势。CRC的发生发展由很多因素导致,遗传、年龄、性别、饮食、代谢综合征等都是CRC发生的高危因素。CRC治疗费用高昂,给社会带来了巨大的经济压力,目前已成为卫生经济学的研究热点之一。大量研究表明,减少高危因素可以降低CRC的发病率和病死率,本文就CRC的危险因素作一综述。

In recent years,the incidence of digestive tract tumors is still high,in which the morbidity and mortality of colorectal cancer(CRC)are increasing,and show a younger trend.The occurrence and development of CRC is caused by many factors,among which heredity,age,diet,sex,metabolic syndrome and so on are the high risk factors of CRC.CRC treatment is costly,which brings huge economic pressure to the society,and has become one of the research hotspots of health economics.A large number of studies have shown that reducing high risk factors can reduce the morbidity and mortality of CRC.This article reviews the risk factors of CRC.