同一体近视性屈光参差双眼黄斑结构及微循环的差异性分析

Differential Analysis of Macular Structure and Microcirculation in Both Eyes of Patients With Myopic Anisometropia

目的探究屈光参差患者双眼黄斑结构及微循环的差异性。方法采用光学相干断层扫描血管成像(OCTA)对44例近视性屈光参差患者双眼的黄斑区视网膜进行扫描,根据对比双眼屈光度数分成高度组和低度组,比较双眼黄斑区视网膜厚度、脉络膜厚度、血管密度以及灌注密度等参数。结果44例患者中,除黄斑中心区及外鼻区外,高度组黄斑中上区、中下区、中颞区、中鼻区、外上区、外下区、外颞区视网膜厚度和中心凹脉络膜厚度均薄于低度组(P均<0.05)。两组视网膜血管密度及灌注密度各区域比较差异均无统计学意义(P均>0.05)。结论在近视性屈光参差患者中,高度眼视网膜厚度大部分区域薄于低度眼,而双眼视网膜血管密度及灌注密度无差异。

Objective To compare the macular structure and microcirculation in both eyes of the patients with myopic anisometropia.Methods Optical coherence tomography angiography(OCTA)was employed to scan the macular areas in both eyes of 44 patients with myopic anisometropia.The patients were assigned into high and low groups based on the refractive diopter,and the parameters such as retinal thickness,choroidal thickness,vascular density,and perfusion density in the macular areas of both eyes were compared between the two groups.Results Other macular areas except the central and external nasal areas and the choroid of the fovea in the high group were thinner than those in the low group(all P<0.05).There was no statistically significant difference in retinal vascular density or perfusion density in different areas between the two groups(all P>0.05).Conclusion In the patients with myopic anisometropia,most areas of the retina in the case of high myopia is thinner than that in the case of low myopia,while there is no difference in retinal vascular density or perfusion density in both eyes.