摘要
As one of the leading causes of cancer deaths worldwide,the pathogenesis of lung cancer is still not completely understood.Bilirubin,a product of heme metabolism,has long been considered a waste product of the body.Increasing evidence suggests that bilirubin has additional antioxidant,anti-inflammatory,and proteasome inhibitory activities.However,the specific role of bilirubin in the formation and development of lung cancer has not been elucidated.
基金
supported by the National Natural Science Foundation of China(No.81602427,82272660,and 81972399)
the Plan on Enhancing Scientific Research in GMU,China(02-410-2302289XM)
Guangdong Province Natural Science Foundation(China)(No.2016A030310281)
Foundation for Higher Education of Guangdong,China(No.2015KQNCX126)
the Natural Science Foundation Research Team of Guangdong Province,China(No.2018B030312001)
the Basic and Applied Basic Research Project of Guangzhou Basic Research Program(China)(No.202201011411).
