心房颤动心室率控制治疗进展

Advances in Ventricular Rate Control Therapy for Atrial Fibrillation

心房颤动(简称房颤)心室率控制治疗包括药物治疗和房室结消融联合起搏的器械治疗。常用于控制心率的药物主要包括β受体阻滞剂、非二氢吡啶类钙通道阻滞剂、洋地黄类以及具有控制心率作用的其他药物。心率控制药物可改善患者症状,而对于房颤的其他作用以及房颤合并不同疾病的药物选择是目前研究的重点。器械治疗作为心率控制的最后手段,可改善房颤症状并提高患者的生活质量。但器械治疗中最适合房颤及房颤合并心力衰竭患者的起搏模式、房颤合并其他疾病心率控制的药物选择以及心率控制药物控制房颤心率以外的其他收益仍需要未来进一步研究明确。

Ventricular rate control therapy for atrial fibrillation includes pharmacological therapy and device therapy with atrioventricular node ablation combined with pacing.Drugs commonly used for heart rate control includeβ-blockers,non-dihydropyridine calcium channel blockers,digitalis,and other drugs with heart rate control effects.While pharmacological heart rate control may improve symptoms,other effects of heart rate control medications on atrial fibrillation and the choice of medications for atrial fibrillation in combination with different diseases are the focus of the current research.Device therapy can be the last resort for heart rate control,which can improve the symptoms and quality of life in the patients with atrial fibrillation.However,the most suitable pacing mode for atrial fibrillation and atrial fibrillation-combined heart failure groups,the choice of heart rate control drugs for atrial fibrillation combined with other diseases,and the benefits of heart rate control drugs other than heart rate control in atrial fibrillation still need to be further clarified in the future studies.