摘要
很多接受整形外科手术的患者合并抑郁症,服用抗抑郁药物是治疗抑郁症的主要手段。抗抑郁药物的作用机制复杂,对整形外科手术患者围手术期的麻醉管理提出挑战。手术前需要停用传统抗抑郁药物,而术前停药会造成停药反应,导致症状加重,新型抗抑郁药物不需要术前停药,但可能会引起围手术期不良反应。深入了解抗抑郁药物作用机制,谨慎制订围手术期麻醉方案,可以避免抗抑郁药物与相关麻醉药物相互作用引发的不良反应,有助于在维持抑郁症患者病情稳定状态下,保证患者安全平稳地度过围手术期。
Many patients undergoing plastic surgery have depression,and taking antidepressants is the main way to treat depression.The mechanism of antidepressants is complex,which challenges the perioperative anesthesia management of the patients undergoing plastic surgery.Traditional antidepressants need to be stopped before surgery,which will cause drug withdrawal reaction and aggravate symptoms.New antidepressants do not need to be stopped before surgery,but may cause perioperative adverse reactions.Deep understanding of the action mechanism of antidepressants and careful formulation of the perioperative anesthesia plan can avoid the adverse reactions caused by the interaction of antidepressants and related anesthetics,which is helpful to ensure the patients to safely and stably pass the perioperative period while maintaining the stable condition of the patients with depression.
作者
陈柯宇
徐瑾
杨冬
CHEN Keyu;XU Jin;YANG Dong(Department of Anesthesiology,Plastic Surgery Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100144,China)
出处
《医学综述》
CAS
2023年第4期778-783,共6页
Medical Recapitulate
关键词
抑郁症
抗抑郁药物
整形外科手术
麻醉管理
Depression
Antidepressants
Plastic surgery
Anesthesia management