急性心肌梗死患者PCI后心律失常影响因素的研究现状

Research Status of Influencing Factors of Arrhythmias in Patients with Acute Myocardial Infarction after PCI

经皮冠状动脉介入治疗(PCI)可及时开通梗死相关动脉、挽救严重缺血或濒死心肌、限制或缩小梗死面积、减轻心室重构、改善心脏功能、降低心脏不良事件发生率,提高急性心肌梗死(AMI)患者的生存率和生活质量。但PCI属于有创性操作,患者常出现心肌缺血再灌注损伤,而心肌缺血再灌注损伤最主要的临床表现是心律失常。虽然大多数再灌注心律失常可自行恢复,无须特殊处理,但恶性心律失常可导致患者血流动力学改变,甚至死亡。因此,早期识别AMI患者PCI后心律失常相关高危因素,可以为患者的治疗提供新思路。

Percutaneous coronary intervention(PCI)can open the infarct related artery in time,save the severely ischemic or dying myocardium,limit or reduce the infarct area,reduce ventricular remodeling,improve cardiac function,reduce the occurrence of adverse cardiac events,and improve the survival rate and quality of life of patients with acute myocardial infarction(AMI).However,PCI is an invasive operation,and myocardial ischemia-reperfusion injury often occurs,with arrhythmia as the main clinical manifestation.Although most ischemia-reperfusion arrhythmias can recover by themselves without special treatment,malignant arrhythmias can lead to hemodynamic changes and even death in patients.Therefore,early identification of high-risk factors related to PCI arrhythmia in AMI patients can provide new ideas for their treatment.