^(131)I在甲状腺功能亢进治疗中的应用进展

Application Progress of ^(131)I in Treatment of Hyperthyroidism

甲状腺功能亢进(简称甲亢)是因甲状腺合成、释放过量甲状腺激素导致机体代谢亢进及交感神经兴奋的甲状腺毒症。目前甲亢的治疗以^(131)I治疗为主,其可减少甲状腺激素释放和负反馈抑制促甲状腺激素的释放,发挥抗甲状腺的作用。目前^(131)I作为碘的放射性同位素在甲亢治疗中应用广泛,治疗方案有其单独治疗、与其他药物联合治疗,且均获取一定的疗效,已积累了大量治疗经验。但这些治疗方案各有优势和不足,仍需对^(131)I治疗方案进行深入研究,以为后续治疗提供指导。

Hyperthyroidism is a kind of thyrotoxicosis caused by excessive thyroid hormone synthesis and release,which leads to hypermetabolism and sympathetic nerve excitation.At present,^(131)I is the main treatment for hyperthyroidism,which can reduce the release of thyroid hormones and inhibit the release of thyroid-stimulating hormone by negative feedback,playing an antithyroid role.At present,^(131)I,as a radioactive isotope of iodine,is widely used in the treatment of hyperthyroidism.The treatment options include its single treatment or combination therapy with other therapies,which can achieve certain therapeutic effects and have accumulated a lot of treatment experience.However,each of these treatment plans has its advantages and disadvantages,and it is still necessary to deepen the research and understanding of ^(131)I treatment plans in order to provide guidance for subsequent treatment.