儿童Peutz-Jeghers综合征内镜下治疗策略

Endoscopic treatment of Peutz-Jeghers syndrome in children

Peutz-Jeghers综合征(Peutz-Jeghers syndrome,PJS)在儿童时期的危害主要是息肉相关并发症,消化道反复生长的、多发的、巨大息肉引起肠套叠或肠梗阻,往往需要多次外科开腹手术治疗。随着儿童消化内镜技术的发展,预防性切除胃肠道息肉,极大地降低了PJS患者在儿童时期的开腹率。文章对儿童PJS患者内镜术前诊断、检查时机、术前评估、治疗原则、治疗技巧及术后管理等进行概述,以期为儿童PJS内镜治疗提供参考。

The main hazards of Peutz-Jeghers syndrome in childhood are polyp-related complications.Repeated,multiple,and large polyps in the digestive tract cause intussuscations or intestinal obstruction,which often requires multiple surgical laparotomy.With the development of pediatric digestive endoscopy,prophylactic resection of gastrointestinal polyps has greatly reduced the opening rate of PJS patients in children.This article summarized the preoperative diagnosis,examination timing,preoperative evaluation,treatment principles,surgical techniques and postoperative management of pediatric PJS patients undergoing endoscopy,with a view to providing references for endoscopic treatment of children with PJS.