基于CAT、COPD-SQ慢阻肺问卷在库车地区COPD诊断效能评价

Evaluation of the diagnostic efficacy of COPD in Kuqa area based on CAT and COPD-SQ chronic obstructive pulmonary disease questionnaires

目的研究慢阻肺筛查问卷检测慢性阻塞性肺疾病(COPD)的临床价值。方法选取库车市人民医院2021年10月至2022年10月收治的COPD患者100例为作为COPD组,同期选取100例非COPD患者作为非COPD组。收集所有研究对象的基线资料、COPD筛查问卷评分、一秒率[第1秒用力呼气容积(FEV_(1))/用力肺活量(FVC)]及FEV_(1)占预计值百分比(FEV_(1)%pred)等资料,绘制ROC曲线确定不同COPD筛查问卷分值和肺功能指标值诊断COPD的敏感度、特异度及AUC面积。结果COPD组的吸烟习惯和GOLD分级中Ⅲ/Ⅳ级比例及合并症占比均明显高于非COPD组(P<0.05)。COPD组的CAT评分和COPD-SQ评分均明显高于非COPD组(P<0.001),FEV_(1)/FVC、FEV_(1)%pred肺功能指标水平均明显低于非COPD组(P<0.001)。COPD患者的CAT评分和COPD-SQ评分均与FEV_(1)/FVC、FEV_(1)%pred呈现明显负相关(P<0.001)。COPD-SQ评分和CAT评分诊断COPD的敏感度分别为83.00%,特异度分别为86.00%、91.00%,AUC面积分别为0.919和0.931。结论CAT评分和COPD-SQ评分在库车地区COPD诊断和病情评估具有较高价值,且与肺功能变化具有明显相关性,对该地区COPD早期预防、规范诊治、长期管控具有重要作用。

Objective To investigate the clinical value of the chronic obstructive pulmonary disease screening questionnaire in testing chronic obstructive pulmonary disease(COPD).Methods A total of 100 COPD patients admitted to Kuqa People’s Hospital from October 2021 to October 2022 were selected as the COPD group,while 100 non-COPD patients were selected as the non-COPD group during the same period.The baseline data,COPD screening questionnaire scores,forced expiratory volume in the first second(FEV_(1))/forced vital capacity(FVC),and percentage of forced expiratory volume in one second to predicted value(FEV_(1)%pred)from all study subjects were collected,and ROC curves were drawn to determine the different COPD screening questionnaire scores and sensitivity,specificity,and AUC area of pulmonary function indicator values in diagnosing COPD.Results The smoking habits,the proportion of Ⅲ/Ⅳ grades in the GOLD grading of and proportion of complication the COPD group were significantly higher than those of the non-COPD group(P<0.05).The CAT score and COPD-SQ score of the COPD group were significantly higher than those of the non-COPD group(P<0.001),while the levels of FEV_(1)/FVC and FEV_(1)%pred pulmonary function indicators were significantly lower than those of the non-COPD group(P<0.001).The CAT score and COPD-SQ score of COPD patients showed a significant negative correlation with FEV_(1)/FVC and FEV_(1)%pred(P<0.001).The sensitivity of the COPD-SQ score and CAT score in diagnosing COPD were 83.00%,and the specificity were 86.00% and 91.00%,and the AUC area were 0.919 and 0.931,respectively.Conclusion The CAT score and COPD-SQ score have high value in the diagnosis and evaluation of COPD in the Kuqa area and are significantly correlated with changes in pulmonary function.They play an important role in early prevention,standardized diagnosis and treatment,and long-term control of COPD in this region.