急性ST段抬高型心肌梗死患者预后预测因素新进展

New advances in prognostic predictive factors for patients with acute ST-segment elevation myocardial infarction

心血管疾病位居我国城乡居民总病死原因的首位,严重威胁着我国人民的生命安全。其中急性ST段抬高型心肌梗死以其发病急、进展快和病死率较高广受关注。虽然直接经皮冠状动脉介入治疗及时开通了病变的血管、减少心肌梗死面积并提高了患者的存活率,但是仍有相当一部分患者预后不佳。本文就最新研究发现的生物标志物和复合指标做一综述,以期为建立新的预测模型提供参考,优化对于急性ST段抬高型心肌梗患者预后的判断,进而制订个体化的治疗方案,降低不良心血管事件的发生率。

Cardiovascular diseases are the leading cause of death among urban and rural residents in China,posing a serious threat to the safety of Chinese people’s lives.Acute ST-segment elevation myocardial infarction has attracted widespread attention due to its urgent onset,rapid progression,and high mortality rate.Although direct percutaneous coronary intervention timely opens diseased blood vessels,reduces myocardial infarction area,and improves patient survival,there are still a considerable number of patients with poor prognosis.This article provides a review of the latest research findings on biomarkers and composite indexes,with the aim of providing a reference for establishing new predictive models,optimizing the judgement on prognosis of patients with acute ST-segment elevation myocardial infarction,and developing personalized treatment protocols,thereby reducing the incidence of adverse cardiovascular events.