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On cancer,stemness,and deep evolutionary homologies

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摘要 Recently,Niculescu published an interesting paper^(1)con-cerning“deep homologies”between the formation of cancer stem cells by polyploidization and reproductive polyploidization of entamoeba.The life cycle of both sys-tems shares the same genetic machinery inherited from the Last Eukaryote Common Ancestor(LECA).This theory claims that cancer is nothing more than the expression of a pre-existing life cycle that was reactivated in“sick and weakened metazoan cell that cannot continue its multi-cellular life and finds itself in the same dead-end situation”.
机构地区 Research Department
出处 《Genes & Diseases》 SCIE CSCD 2023年第4期1143-1144,共2页 基因与疾病(英文)
关键词 CANCER HOMOLOG NOTHING
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