摘要
Recently,p.Glu1121Ter in PLXNA1 was identified as po-tential cause for a patient with parkinsonism.However,no further replication has been conducted in a wider range of Parkinson’s disease(PD)cohorts.To evaluate the genetic association of PLXNA1 with PD,we systematically analyzed the rare protein-coding variants in 1,245 Chinese patients with whole exome sequencing.
基金
supported by the funding of the National Key Research and Development Program of China(No.2021YFC2501200)
the Sichuan Science and Technology Program(China)(No.2022ZDZX0023,No.2021YJ0415)
the National Natural Science Foundation of China(No.81901294,81871000).
