双镜联合治疗在胃肠间质瘤中的应用进展

Progress in the application of laparoscopic and endoscopic cooperative surgery in gastrointestinal stromal tumors

胃肠间质瘤(GIST)是最常见的消化道间叶组织肿瘤,具有潜在恶性。手术是治疗GIST的首选方法,双镜联合(LECS,即腹腔镜联合内镜)是一种治疗GIST的新型手术方法,包括经典LECS、倒置LECS和腹腔镜辅助内镜全层切除术等多种术式。与单纯内镜治疗和单纯腹腔镜治疗相比,双镜联合治疗GIST可以充分发挥腹腔镜和内镜各自的优势,具有定位准确、病灶切除完整和预后良好等优点。目前,LECS适用于肿瘤直径<50 mm且用传统内镜手术方法无法完全切除的GIST,未来可以继续加以探索并扩大其临床应用,最终使患者受益。

Gastrointestinal stromal tumor(GIST)is the most common mesenchymal tumor among gastrointestinal tumors,with an inherent potential for malignancy.The primary approach to addressing GIST remains surgical intervention.Laparoscopic and endoscopic cooperative surgery(LECS)has emerged as an innovative treatment approach for GIST.LECS includes various techniques,such as classic LECS,inverted LECS,and laparoscopic-assisted endoscopic full-thickness resection,all of which aim to combine the advantages of laparoscopy and endoscopy.This treatment offers benefits such as accurate localization,complete lesion removal,and a good prognosis.Generally,LECS can be used for GIST with a tumor diameter less than 50 mm,which cannot be completely removed through traditional endoscopic surgery.The clinical application of LECS deserves further exploration and expansion in the future,ultimately benefiting patients.