济宁市兖州区18~69岁居民代谢综合征患病现况及影响因素分析

Analysis on current status and influencing factors of metabolic syndrome in people aged 18 to 69 years old in Yanzhou district, Jining city

目的 了解山东省济宁市兖州区18~69岁居民代谢综合征(MS)的患病情况,并探讨相关影响因素,为制定MS的预防控制策略及措施提供基础数据。方法 于2021年10-12月采用多阶段分层随机抽样的方法,对山东省济宁市兖州区18~69岁常住居民进行问卷调查,收集研究对象的基本信息。对研究对象进行体格检查,测量身高、体质量、腰围、收缩压(SBP)和舒张压(DBP),计算体质量指数(BMI)。采集研究对象指尖血测定空腹血糖及糖负荷后2 h血糖,采集清晨空腹静脉血测定甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)等生化指标。分析MS患病率及影响因素。结果 收集山东省济宁市兖州区18~69岁居民1 898例,诊断MS患者622例,患病率为32.8%(622/1 898)。不同年龄、文化程度、婚姻状况、饮酒和BMI人群MS患病率不同(χ^(2)值分别为124.87、36.54、36.03、5.00、146.95,P<0.05),年龄方面以60~69岁年龄MS患病率最高(44.2%),文化程度方面以小学文化程度者MS患病率最高(41.6%),婚姻状况方面以丧偶/离异/分居者MS患病率最高(49.2%),饮酒者MS患病率(31.1%)高于从不饮酒者(36.2%),肥胖者MS患病率(53.7%)高于超重(34.1%)和BMI正常或偏低者(16.6%)。多因素logistic回归分析显示,年龄(O R=1.051,95%CI:1.040~1.063)、饮酒(O R=1.290,95%CI:1.035~1.068)、BMI(O R=1.158,95%CI:1.124~1.194)是MS患病的主要影响因素(P<0.05或P<0.01)。结论 山东省济宁市兖州区18~69岁居民MS患病率较高,年龄、文化程度、婚姻状况、饮酒以及BMI为MS患病的主要影响因素。

Objective To investigate the prevalence of metabolic syndrome(MS)among inhabitants aged 18 to 69 in Yanzhou district,Jining city,Shandong province,and to explore the related influencing factors,so as to offer fundamental data for the development of MS prevention and control strategies and methods.Methods In October-December 2021,a questionnaire survey was conducted in Yanzhou district,Jining city,Shandong province,utilizing multi-stage stratified random sampling to obtain basic information on study participants aged 18 to 69 years.The study volunteers were examined physically,and their height,body mass,waist circumference,systolic and diastolic blood pressure(SBP)and body mass index(BMI)were measured.Fasting blood glucose and 2 h blood glucose after glycemic load were determined using fingertip blood,and fasting venous blood was collected in the early morning to determine triglycerides(TG),high-density lipoprotein cholesterol(HDL-C),and other biochemical indicators.The prevalence of MS as well as the major contributing factors were investigated.Results A total of 1898 cases of permanent residents aged 18-69 years in Yanzhou district were collected for investigation and analysis,of which 622 patients with metabolic syndrome were diagnosed,with a prevalence of MS of 32.8%(622/1898).The prevalence of MS was different in different age,education,marital status,alcohol consumption and BMI groups(χ^(2)=124.87,36.54,36.03,5.00,146.95,respectively,P<0.05),and the highest prevalence of MS was found in the age group of 60-69 years old(44.2%),the highest prevalence of MS was found in the people with primary education(41.6%),MS prevalence was highest among those who were widowed/divorced/separated(49.2%),MS prevalence was higher among those who consumed alcohol(31.1%)than those who never consumed alcohol(36.2%),and MS prevalence was higher among those who were obese(53.7%)than those who were overweight(34.1%)and those who had normal or low body mass(16.6%).Multivariate logistic regression analysis showed that age(OR=1.051,95%CI:1.040-1.063),alcohol consumption(OR=1.290,95%CI:1.035-1.068),and BMI (OR=1.158,95%CI:1.124-1.194)were the main influencing factors for MS.Conclusion The prevalence of MS is high among residents aged 18-69 years in Yanzhou district,Jining city,Shandong province,different age,education level,marital status,alcohol consumption,and body mass index are the main factors influencing the prevalence of MS.