超声介入下囊肿内注射不同硬化剂治疗肝囊肿的效果分析

Effect Analysis of Intralesional Injection of Different Sclerosing Agents Under Ultrasound Intervention in Treatment of Hepatic Cysts

目的:探讨超声介入下囊肿内注射不同硬化剂治疗肝囊肿的效果。方法:选取2020年2月—2022年10月黄冈市团风县人民医院收治的86例肝囊肿患者作为研究对象,采用抽签法分为两组,各43例。两组均采用超声引导下注射硬化剂治疗,对照组注射无水乙醇硬化剂,观察组注射聚桂醇硬化剂。比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P=0.013)。治疗后3、6个月,观察组囊肿体积小于对照组,差异有统计学意义(P<0.001)。治疗后6个月,观察组丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素水平低于对照组,差异有统计学意义(P<0.001)。观察组不良反应总发生率低于对照组,差异有统计学意义(P=0.013)。结论:超声介入下囊肿内注射聚桂醇硬化剂治疗肝囊肿的效果显著,可缩小囊肿体积,促进肝功能改善,降低不良反应发生率。

Objective:To investigate the effect of intralesional injection of different sclerosing agents under ultrasound intervention in treatment of hepatic cysts.Methods:A total of 86 patients with hepatic cysts admitted to Huanggang Tuanfeng County People's Hospital from February 2020 to October 2022 were selected as the study subjects.They were divided into two groups with 43 cases in each group by lottery method.Both groups were treated with ultrasound-guided injection of sclerosing agents,the control group was injected with dehydrated alcohol sclerosing agent,and the observation group was injected with lauromacrogol sclerosing agent.The treatment effects were compared between the two groups.Results:The total effective rate of treatment in the observation group was higher than that in the control group,and the difference was statistically significant(P=0.013).At 3 and 6 months after treatment,the cyst volume in the observation group was smaller than that in the control group,and the difference was statistically significant(P<0.001).At 6 months after treatment,the levels of alanine aminotransferase,aspartate aminotransferase and total bilirubin in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.001).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P=0.013).Conclusion:The intralesional injection of lauromacrogol sclerosing agent under ultrasound intervention is effective in treatment of hepatic cysts,which can reduce the volume of cysts,promote the improvement of liver function,and reduce the incidence of adverse reactions.