皮层体感诱发电位在脊髓损伤康复评估中的应用

Application of cortical somatosensory evoked potential in rehabilitation assessment of spinal cord injury

脊髓损伤(spinal cord injury,SCI)作为高死亡率、高致残率的常见中枢神经系统疾病,给患者、家庭、社会带来巨大的经济负担,在临床和科研工作中选择客观、敏感的评估工具反映患者康复效果的变化情况具有重要意义。皮层体感诱发电位(cortical somatosensory evoked potential,CSEP)作为一种无创的神经电生理检测方法,相较于体格检查、影像学检查、康复评定量表等传统评定方法更客观、有效。本文结合临床实验及动物实验对CSEP在SCI康复效果评价中的应用进行综述,以期为SCI患者的早期诊断、康复治疗和康复效果评估提供参考。

Spinal cord injury(SCI),as a common central nervous system disease with high mortality and disability rates,brings huge economic burden to patients,families,and society.It is of great significance to choose objective and sensitive evaluation tools in clinical and scientific work to reflect the changes in patient rehabilitation outcomes.Cortical somatosensory evoked potential(CSEP),as a non-invasive neurophysiological detection method,is more objective and effective than traditional assessment methods such as physical examination,imaging examination,and rehabilitation assessment scales.This article reviews the application of CSEP in the evaluation of SCI rehabilitation effects through clinical and animal experiments,in order to provide reference for early diagnosis,rehabilitation treatment,and rehabilitation effect evaluation of SCI patients.