蛋白质组学和代谢组学技术在蜂产品中的应用研究进展

Research Progress in the Application of Proteomics and Metabolomics in Bee Products

蜂产品因其具有丰富的营养成分和多种生物活性,受到越来越多消费者的欢迎。但蜂产品掺假造假的问题日益突出,且其生物活性的机制尚未充分阐明。蛋白质组学和代谢组学技术可以完整、全面地描述蛋白质和小分子代谢物的整体特征,近年来在蜂产品领域的应用较为广泛,已成为解决蜂产品掺假造假问题和阐明其生物活性机制的有力手段。本文综述了蛋白质组学和代谢组学技术在蜂产品中的应用研究进展,在概述蛋白质组学和代谢组学具有同时鉴定全组分和筛选特征标志物等优势的基础上,针对其在蜂产品成分鉴定、鉴别和鉴伪、生物活性机制研究中的应用进行了详细阐述,并对存在的问题进行了分析,对后续研究方向进行了展望,以期为组学技术在蜂产品研究中的广泛深入应用提供参考。

Bee products are gaining increasing popularity among consumers for their high nutritional value and various biological activities.However,adulteration is becoming a prominent problem in the production and sale of bee products,and the mechanisms underlying their biological activities have not been fully elucidated.Proteomics and metabolomics can provide complete and comprehensive descriptions on the overall characteristics of proteins and small-molecular metabolites.In recent years,these two omics approaches have been widely used in the field of bee products,and become a powerful means to solve the problem of adulteration in bee products and elucidate the mechanisms underlying their biological activities.This paper reviews the research progress in the application of proteomics and metabolomics in bee products.Based on an overview of the advantages of proteomics and metabolomics in simultaneous identification of whole components and screening of characteristic markers,the paper also summarizes their applications in the identification of components,discrimination and authentication,and elucidation of mechanisms for biological activities of bee products in detail.In addition,the existing problems are analyzed and the future research directions are proposed.The paper is expected to provide a reference for extensive and in-depth application of omics technologies in the research of bee products.