个体化营养干预对慢性肾衰竭透析患者营养状况及生活质量的影响

Effect of Individualized Nutrition Intervention on Nutritional Status and Quality of Life of Dialysis Patients with Chronic Renal Failure

目的:探讨个体化营养干预对慢性肾衰竭透析患者营养状况及生活质量的影响。方法:收集2021年2月—2022年9月在东南大学附属中大医院溧水分院进行透析的60例慢性肾衰竭患者为研究对象,将60例患者随机均分观察组和对照组各30例,两组患者间年龄、性别、方式、透析病程均无差异(P>0.05)。对照组患者进行常规临床治疗和营养宣教,观察组患者在此基础上给予个体化营养干预,比较干预前后2组血清营养指标,包括血清白蛋白(ALB)、前白蛋白(PA)、血红蛋白(HGB)、转铁蛋白(TRF),NRS 2002评分及生活质量(SF-36评分)的变化。结果:经透析及干预后,两组患者血清ALB、PA、HGB、TRF,NRS 2002评分,以及SF-36中生理健康总评分、心理健康总评分及总评分均较干预前显著增高,而营养风险发生率均显著降低,且个体化营养干预组患者上述改善情况显著优于对照组(均有P<0.05)。结论:对慢性肾衰竭透析患者进行个体化营养干预,可显著降低营养风险发生率,使患者血清营养指标增高,改善患者生活质量。

【Objective】To investigate the effects of individualized nutritional interventions on the nutritional status and quality of life of dialysis patients with chronic renal failure.【Method】From February 2021 to September 2022,60 patients with chronic renal failure who were on dialysis at the Lishui Branch of the Affiliated Hospital of Southeast University were collected as the study subjects,and the 60 patients were randomly divided into 30 patients in the observation group and 30 patients in the control group,and there was no difference in age,gender,mode and duration of dialysis between the two groups(P>0.05).Patients in the control group were given conventional clinical treatment and nutrition education,while patients in the observation group were given individualized nutrition interventions on this basis.The changes in serum nutritional indicators,including serum albumin(ALB),prealbumin(PA),hemoglobin(HGB)and transferrin(TRF),NRS 2002 scores and quality of life(SF-36 scores)were compared between the two groups before and after the intervention.【Result】After dialysis and intervention,serum ALB,PA,HGB and TRF,NRS 2002 score,and total physical health score,total mental health score and total score in SF-36 were significantly higher in both groups than before the intervention,while the incidence of nutritional risk was significantly lower in both groups,and the above improvements were significantly better in the individualized nutrition intervention group than in the control group,all with P<0.05.【Conclusion】Individualized nutritional interventions for dialysis patients with chronic renal failure can significantly reduce the incidence of nutritional risk,result in increased serum nutritional parameters and improve the quality of life of patients.