硫酸沙丁胺醇雾化吸入溶液治疗毛细支气管炎患儿的药理机制及疗效研究

Pharmacological Mechanism and Efficacy of Salbutamol Sulfate Nebulized Inhalation Solution in the Treatment of Children with Bronchiolitis

分析硫酸沙丁胺醇雾化吸入溶液治疗毛细支气管炎患儿的药理机制及疗效。选取2022年1月—2023年6月六盘水市水城区妇幼保健院收治的90例毛细支气管炎患儿为研究对象,按照治疗方式不同将患儿分为两组,每组各45例。对照组实施常规+布地奈德治疗,观察组实施常规+布地奈德+硫酸沙丁胺醇雾化吸入溶液治疗,对比两组患儿治疗效果。结果显示,观察组治疗总有效率高于对照组(P<0.05),肺功能指标和炎性因子水平均优于对照组(P<0.05),临床症状改善时间显著短于对照组(P<0.05)。研究发现,硫酸沙丁胺醇雾化吸入溶液具有扩张支气管的作用,有助于加快患儿临床症状改善,减轻炎性因子对患儿气道的刺激,提高疗效并改善患儿肺功能,患儿出现的不良反应较少,具有较高临床应用与推广价值。

Analyze the pharmacological mechanism and efficacy of salbutamol sulfate nebulized inhalation solution in the treatment of children with bronchiolitis.90 children with bronchiolitis admitted to Liupanshui Shuicheng District Maternal and Child Health Hospital from January 2022 to June 2023 were selected as the research subjects.The children were divided into two groups according to different treatment methods,with 45 cases in each group.The control group received routine+budesonide treatment,while the observation group received routine+budesonide+salbutamol sulfate nebulized inhalation solution treatment.The treatment effects of the two groups of children were compared.The results showed that the total effective rate of the observation group was higher than that of the control group(P<0.05),and the lung function indicators and inflammatory factor levels were better than those of the control group(P<0.05).The clinical symptom improvement time was significantly shorter than that of the control group(P<0.05).Research has found that salbutamol sulfate nebulized inhalation solution has the effect of dilating the bronchi,helping to accelerate the improvement of clinical symptoms in children,reduce the stimulation of inflammatory factors on the airways of children,improve therapeutic effects,and improve lung function in children.Children have fewer adverse reactions,and have high clinical application and promotion value.