基于浊毒理论探讨代谢综合征病机及治疗

Discussion on pathogenesis and treatment of metabolic syndrome based on turbid toxin theory

代谢综合征属于中医学“肥胖”“消渴”“脾瘅”等范畴,是以多种代谢异常在同一个体集结出现,包括肥胖、高血糖、血脂异常、高血压以及高尿酸血症等为表现的临床综合征。“浊毒”是由于脏腑功能失常,导致机体产生的生理、病理产物不能及时排出,蕴积体内而化生的致病因素。浊毒致病机体多有面色晦浊、腹胀满、小便浑浊、大便黏腻不爽、黄腻苔、滑数脉等表现。浊毒与代谢综合征的发病机制,在微观和宏观上具有对应性。文章从浊毒与代谢综合征的发病机制出发,对其临床治疗的共同点进行了综述。

Metabolic syndrome falls into the categories of obesity,diabetes and spleen disease in traditional Chinese medicine,and is manifested by various metabolic abnormalities in an individual,including obesity,hyperglycemia,dyslipidemia,hypertension and hyperuricemia.The turbid toxin is a pathogenic factor caused by visceral dysfunction,which leads to the accumulation of physiological and pathological wastes that fail to be eliminated from the body in time.People with turbid toxin are manifested by dull and cloudy complexion,abdominal distension,turbid urine,sticky stool,yellow greasy coating,slippery pulse,etc.The turbid toxin corresponds to the pathogenesis of metabolic syndrome at both micro and macro levels.This paper intends to explore the correlations between the turbid toxin and the pathogenesis of metabolic syndrome and make a review with relevant clinical treatment.