“五脏同调”理论在改善大肠癌化疗后癌因性疲乏中的应用

Application of the theory of five visceras in harmony in ameliorating cancer-related fatigue after chemotherapy for colorectal cancer

随着当今社会生活水平的逐渐提高,大肠癌的发病率也呈上升趋势,其发病率及病死率均较高,术后绝大多数患者会选择化疗治疗。但化疗后易出现严重不良反应,癌因性疲乏就是其中之一,严重影响患者的生活质量,甚至影响化疗治疗的顺利进行,从而影响整体疗效。山东中医药大学附属医院肿瘤科刘寨东教授认为,人体是一个有机的整体,五脏之间相通相连,是一个完整的整体,其生理功能各有不同,任何一脏功能受损都会对整体产生影响,也会影响机体其他部分的机能。故在临床上治疗大肠癌癌因性疲乏时,除了从大肠自身出发之外,更要着重从肝、心、脾、肺、肾五脏分别与大肠生理、病理及经络上的相互关系角度进行分析研究。刘寨东教授以中医经典古籍作为依据,认为五脏都对大肠生理及病理机制发挥作用,以“五脏同调”理论为基础,创立了经验方黄芪太子饮,临床应用取得了良好疗效。文章结合案例,介绍刘教授治疗大肠癌化疗后癌因性疲乏经验,以期为临床提供参考。

With the gradual improvement of living standards in today’s society,the incidence of colorectal cancer is also on the rise,and its morbidity and mortality are high.Most patients after surgery will choose chemotherapy.However,severe adverse reactions are prone to occur after chemotherapy,and cancer-related fatigue is one of them.It seriously affects theW quality of life of patients,and even affects the smooth progress of chemotherapy treatment,thus affecting the overall curative effect.Professor LIU Zhaidong of the Oncology Department of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine believes that the human body is an organic whole,and that the five visceras are connected to form a complete whole.The overall effect will also affect the function of other parts of the body.Therefore,in the clinical treatment of cancer-related fatigue in colorectal cancer,in addition to starting from the large intestine itself.It is more important to analyze and study the relationship between the liver,heart,spleen,lung,kidney and the large intestine in terms of their physiology,pathology,and meridians.Based on the classics of traditional Chinese medicine,Professor LIU Zhaidong believes that the five visceras all play an impact on the physiological and pathological mechanisms of the large intestine.Based on the theory of five visceras in harmony,the professor creates the empirical prescription,the Huangqi Taizi decoction(黄芪太子饮),which has achieved good clinical effects.This article combines a case to introduce Professor LIU’s experience in treating cancer-related fatigue after chemotherapy for colorectal cancer,in order to provide a reference for clinical practice.