3Bovill JG, Sebel PS, Blackburn CL, et al. The pharmacokinet- ics of alfentanil (R39209) : a new opioid analgesic [ J]. Anes- thesiology, 1982,57(6) :4-39-443.
4. Sharer A, Sung ML, White PF. Pharmacokinetics and pharma- codynamics of alfentanil infusions during general anesthesia [ J ]. Anesth Analg, 1986,65(10) : 1021-1028.
6Shand DG, Desjardins RE, Bjornsson TD, et al. The method of separate exponentials: a simple aid to devising intravenous drug-loading regimens [ J ]. Clin Pharmacol Ther, 1981,29 (4) : 542-547.
7Miller RD, Eriksson LI, Fleisher LA, et al. Miller's Anesthe- sia [ M ]. 6th ed. Philadelphia: Elsevier Churchill Livingstone, 2005 : 400-402.
8Camu F, Gepts E, Rucquoi M, et al. Pharmacokinetics of al- fentanil in man [ J ]. Anesth Analg, 1982,61 (8) : 657-661.
9Bista SR, Lobb M, Haywood A, et al. Development, valida- tion and application of an HPLC-MS/MS method for the determi- nation of fentanyl and nor-fentanyl in human plasma and saliva [ J]. J Chromatogr B Analyt Technol Biomed Life Sci,2014,960 (6) :27-33.
