摘要
心脏手术相关的急性肾损伤(cardiac surgery‑associated acute kidney injury,CSA‑AKI)是心脏手术后的主要并发症之一,其对患者的近期和远期生存率都有负面影响。有研究显示,心脏疾病患者肾静脉淤血与肾功能损伤和病死率相关,CVP作为静脉淤血的量化指标,高CVP被确定为CSA‑AKI的独立危险因素。文章分析有关静脉淤血与CSA‑AKI的相关性及其机制的文献资料,描述了心脏手术中肾静脉淤血、肾静脉淤血导致急性肾损伤(acute kidney Injury,AKI)的机制以及AKI的防治。肾静脉淤血导致AKI的机制还需要深入研究和不断探索,以进一步改善心脏手术患者的生存质量和长期转归。
Cardiac surgery‑associated acute kidney injury(CSA‑AKI)is one of the major complications after cardiac surgery,which can exert negative impact on both near‑term and long‑term survival.Some studies have shown that renal venous congestion is as‑sociated with renal function injury and mortality in patients with cardiac disease.Using central venous pressure(CVP)as a quantitative indicator of venous congestion,they considered high CVP as an independent risk factor for CSA‑AKI.The current review summarizes the correlation between venous congestion and CSA‑AKI and the mechanisms involved.This paper describes the renal vein congestion during cardiac surgery,the mechanism by which renal vein congestion causes acute kidney injury(AKI)and the prevention and treat‑ment of AKI.The mechanism of AKI still needs further studies and continuous exploration,in order to improve the quality of life and long‑term outcome of patients after cardiac surgery.
作者
胡兰鑫
葛亚力
Hu Lanxin;Ge Yali(Department of Anesthesiology,Perioperative and Pain Medicine,Nanjing First Hospital,Nanjing Medical University,Nanjing 210006,China)
出处
《国际麻醉学与复苏杂志》
CAS
2023年第10期1086-1089,共4页
International Journal of Anesthesiology and Resuscitation
基金
南京市卫生科技发展专项资金(YKK22109)。
关键词
急性肾损伤
心脏手术
静脉淤血
Acute kidney injury
Cardiac surgery
Venous congestion