电磁环境生物效应的分子动力学基础

Fundamentals of Molecular Dynamics on Biological Effects of Electromagnetic Environment

随着电磁环境越来越复杂,电磁辐射生物效应愈加受到人们的关注,尤其是非热效应的作用至今仍然没有完全搞清楚。文章采用分子动力学模拟方法,研究微波对肌肽(生物活性分子)活性位点碰撞的空间方位和动能的影响,提出了微波后极化效应,以此阐述电磁环境生物效应的分子动力学机理。计算结果表明:随着电场强度的增大,线极化下碰撞总数增加了2.9%~13.3%,而圆极化的碰撞总数增加了2.4%~11.2%;特定空间角度范围内,线极化微波下碰撞的概率最大增加了131.3%,圆极化微波下碰撞的概率最大增加了47.1%。该研究有助于揭示电磁环境生物效应的分子机理。

As the electromagnetic environment is becoming more and more complex,the biological effects of electromagnetic radiation are getting more and more attention,especially electromagnetic non-thermal effects is still not fully understood.In this paper,the influence of microwave on the spatial orientation and kinetic energy of carnosine(bioactive molecule)collision was studied by molecular dynamics simulation method.The microwave post-polarization effect was proposed to illustrate the molecular dynamics mechanism of biological effects in electromagnetic environment.The results show that with the increase of microwave intensity,the total number of collisions with linear polarization increases by 2.9%to 13.3%,while the total number of collisions with circular polarization increases by 2.4%to 11.2%.In the range of specific spatial angles,the probability of collision with linear polarization microwave field increased by a maximum of 131.3%,and the probability of collision with circular polarization microwave field increased by a maximum of 47.1%.This study will help to reveal the molecular mechanism of the biological effects of electromagnetic environment.